Embryonic Development of the Testis
نویسندگان
چکیده
Testicular development is a very interesting aspect of male reproduction and fertility. The primordial germ cells migrate from yolk sac to the genital ridge along the wall of the hindgut and the dorsal mesentery to ultimately settle in the genital ridge that would give rise to testes. Sex-determining region of the Y chromosome (SRY) is the principal driver of testes development. Testes development culminates into descent of fully formed testes in the scrotum, which is necessary for facilitating spermatogenesis. Failure of testicular descent results in their retention in the inguinal canal or abdomen, often associated with azoospermia and infertility. This chapter provides a brief overview of the process of testicular development and descent with a glimpse of the consequences of the failure of testicular descent.
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